Resveratrol, an ingredient found in grapes and red wine, has often been linked to the explanation regarding the term 'French paradox', the puzzling fact that the French suffer less from heart related diseases, even though they enjoy a higher-fat diet than most Americans do. This has led to research by scientists, who have now taken an interest in exploring how resveratrol might help in extending lifespan of a human.

They hope to use resveratrol grape juice or resveratrol based compound to provide the same effects as that of a severely restricted diet, which is supposed to extend lifespan of humans. This is a low level caloric intake diet which activates a class of proteins, called sirtuin which in turn control metabolism; there are few other natural substances that can activate sirtuin, but resveratrol grape juice is particularly potent at triggering sirtuins.

This new interest that researchers have found in resveratrol grape juice, has led to several breakthroughs. The scientists at Harvard University have proven that resveratrol grape juice helps in extending lifespan by controlling the activity of a gene associated with aging generally present in all life forms. It has been practically demonstrated that while middle-aged mice which fed on a high-calorie diet suffered the deadly effects of obesity such as metabolic changes resembling diabetes, liver and cardiac damage, and premature death. Mice which were fed with resveratrol along with the same high-calorie diet demonstrated healthy changes in their physiology, which were found in mice fed with standard diet.
The reason behind all age-related illness is oxidative stress. It is responsible for numerous disease processes and for aging itself. Resveratrol grape juice shows powerful antioxidant abilities capable of providing benefits for human health beyond imagination.

Scientists reports suggest that resveratrol grape juice improves the oxidation rate of dangerous low-density lipoprotein (LDL) and and helps in filtering out harmful hydroxyl radicals. Resveratrol grape juice also facilitates in maintenance of glutathione levels, our body's major antioxidants. According to one of the prominent resveratrol investigators, resveratrol grape juice is a very effective free-radical filters with many effects capable of affecting not only longevity but general health in common.

Resveratrol grape juice is capable of improving health and reduce the rate of aging process affecting many mechanisms such as potent antioxidant effects, capability to improve energy production at cellular level, and the ability to improve patterns of gene expression in the same manner as that of a low calorie-diet restriction would provide.

A word of caution though, few side effects such as increased sensitivity to temperature variations, increased adult acne have been noticed. So it is advisable to visit a doctor under such situations.